[Controlled arterial hypotension produced by nitroprusside combined with neuroleptics].

Ganglioplegic drugs, including trimetaphan, have been imperfect agents of arterial hypotension, liable to produce tachyphylaxis, and not blocking intercurrent attacks of adrenergic hypertension the dose is inconstant and reversibility sometimes doubtful. The association of neuroleptics, in particulier promazines, permits an appreciable economy in dosage, stabilises the curves of hypotension, with the disadvantage of blocking normalisation of blood pressure. Sodium nitroprusside does not have the disadvantage of ganglioplegic drugs.

[Involvement or non-involvement of intracranial pressure with arterial pressure].

In this experiment carried out on dogs, the authors demonstrate with the aid of very expressive illustrations that rapid variations in arterial pressure are accompanied by variations of the intracranial pressure. The latter may be, depending on the case, either in the same direction or inverse, according to the local cerebral vasomotor response accompanying the systemic arterial hypertension.