Effectiveness and safety of oral anticoagulant therapy in a real-world cohort with atrial fibrillation: The SIESTA-A study protocol.

Introduction: Oral anticoagulants (OACs) are first-line drugs for stroke prevention in patients with atrial fibrillation (AF). The introduction of new lines of therapy with direct oral anticoagulants (DOACs) has led to a decreased use of vitamin K antagonists (VKAs). Comparative analyses of DOACs in clinical trials are scarce and the comparator has mostly been warfarin.

Electrochemotherapy for the Treatment of Unresectable Locoregionally Advanced Cutaneous Melanoma: A Systematic Review.

Electrochemotherapy is a therapeutic option for the treatment of cutaneous and subcutaneous metastases from melanoma and other tumors. The procedure consists of the administration of anticancer drugs followed by locally applied electrical impulses to achieve an effect known as electroporation, which facilitates entry into the cytosol of drugs that cannot cross the cell membrane. The aim of this review is to evaluate the evidence that supports the use of electrochemotherapy as a therapeutic strategy in melanoma.

Hospital mortality in acute coronary syndrome: differences related to gender and use of percutaneous coronary procedures.

Background: To identify differences among men and women with acute coronary syndrome in terms of in-hospital mortality, and to assess whether these differences are related to the use of percutaneous cardiovascular procedures.

Methods: Observational study based on the Minimum Basic Data Set. This encompassed all episodes of emergency hospital admissions (46,007 cases, including 16,391 women and 29,616 men) with a main diagnosis of either myocardial infarction or unstable angina at 32 hospitals within the Andalusian Public Health System over a four-year period (2000-2003).

[Differences between women's and men's access to interventional cardiovascular procedures at public hospitals in Andalusia (Spain)].

Introduction And Objectives: The aim of this study was to determine whether there are differences between women's and men's access to coronary revascularization procedures for acute coronary syndrome in Andalusia, Spain.

Methods: This observational multicenter study was based on the Andalusian Minimum Basic Data Set (CMBDA). The study included all hospitalizations at public hospitals in the period 2000-2003 that involved emergency admission and in which the principal diagnosis was acute myocardial infarction or unstable angina.