Publications by authors named "M J A Siddique"

Pseudomonas aeruginosa (P. aeruginosa) is a major pathogen associated conditions like septicaemia, respiratory disorders, and diarrhoea in poultry, particularly in Japanese quail (Coturnix japonica). The infection causes huge economical losses due to its high transmissibility, mortality and zoonotic potential.

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Background: TCP proteins are plant-specific transcription factors that play essential roles in various developmental processes, including leaf morphogenesis and senescence, flowering, lateral branching, hormone crosstalk, and stress responses. However, a comprehensive analysis of genome-wide TCP genes and their expression patterns in melon is yet to be done.

Objective: The present study aims to identify and analyze the TCP genes in the melon genome and understand their putative functions.

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Maize is a cornerstone of global agriculture, essential for food security, livestock feed, and industrial uses. With the increasing demand for maize due to population growth and changing dietary patterns, there is a pressing need to enhance maize production. Hybridization is a strategic approach for developing high-yielding and stress-tolerant maize varieties and evaluating these hybrids in specific environmental conditions is vital for optimizing yield and adaptability.

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Background/objectives: Full immunization coverage in Pakistan remains suboptimal at 66%. An in-depth assessment is needed to understand the long-term trends in immunization and identify the extent of defaulters and associated risk factors of them being left uncovered by the immunization system.

Methods: We conducted a 5-year analysis using the Government's Provincial Electronic Immunization Registry data for the 2018-2023 birth cohorts in Sindh province.

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Article Synopsis
  • Adjuvants like QS-21 are essential for boosting vaccine effectiveness, but QS-21 faces challenges such as limited availability, complex synthesis, and toxicity.
  • Researchers are working on creating simpler and safer analogues of QS-21 that maintain strong immunogenic properties.
  • The analogues VA05 and VA06 show promising results, generating similar antibody responses as QS-21 while being less toxic, making them potential candidates for better vaccine adjuvants.
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