Publications by authors named "M Izumitani"
Article Synopsis
- A nationwide surveillance in Japan studied the antimicrobial susceptibility of bacteria in acute uncomplicated cystitis, focusing on E. coli, K. pneumoniae, and S. saprophyticus, between April 2020 and September 2021.
- The study isolated 823 bacterial strains from urine samples of 848 patients, with a majority being E. coli (92.9%), and determined susceptibility to 18 antibacterial agents.
- Results showed a concerning increase in fluoroquinolone-resistant E. coli and extended-spectrum β-lactamase (ESBL)-producing E. coli, especially in postmenopausal women, highlighting the need for clinicians to adapt their antibiotic choices due to rising resistance rates.
Neisseria gonorrhoeae is one of the important pathogens of sexually transmitted infections. N. gonorrhoeae is rapidly becoming antimicrobial resistant, and there are few drugs that are effective in the initial treatment of gonorrhea.
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- The Urogenital Sub-committee and Surveillance Committee of various Japanese health organizations conducted a nationwide study to assess how susceptible Chlamydia trachomatis is to different antibiotics by collecting clinical samples from 26 hospitals between May 2016 and July 2017.
- The study measured the minimum inhibitory concentrations (MICs) for a range of antibiotics, finding no resistant strains to fluoroquinolones, tetracyclines, or macrolides, while solithromycin showed particularly favorable MIC values.
- However, the MIC for azithromycin was slightly higher than in previous reports, suggesting the need for ongoing monitoring of its susceptibility.
Second nationwide surveillance of bacterial pathogens in patients with acute uncomplicated cystitis conducted by Japanese Surveillance Committee from 2015 to 2016: antimicrobial susceptibility of Escherichia coli, Klebsiella pneumoniae, and Staphylococcus saprophyticus.
J Infect Chemother
June 2019
The Japanese Surveillance Committee conducted a second nationwide surveillance of antimicrobial susceptibility patterns of uropathogens responsible for acute uncomplicated cystitis (AUC) in premenopausal patients aged 16-40 years old at 31 hospitals throughout Japan from March 2015 to February 2016. In this study, the susceptibility of causative bacteria (Escherichia coli, Klebsiella pneumoniae, Staphylococcus saprophyticus) for various antimicrobial agents was investigated by isolation and culturing of organisms obtained from urine samples. In total, 324 strains were isolated from 361 patients, including E.
View Article and Find Full Text PDFNationwide surveillance of bacterial pathogens from patients with acute uncomplicated cystitis conducted by the Japanese surveillance committee during 2009 and 2010: antimicrobial susceptibility of Escherichia coli and Staphylococcus saprophyticus.
J Infect Chemother
June 2013
Article Synopsis
- A nationwide surveillance study conducted in Japan from April 2009 to November 2010 examined antimicrobial susceptibility patterns of uropathogens causing acute uncomplicated cystitis in women, involving 43 hospitals.
- The study identified E. coli as the most common bacteria (77.8%) in urine samples, with significant occurrences of S. saprophyticus in premenopausal women, while also analyzing their resistance to 19 antimicrobial agents.
- Results indicated high susceptibility of E. coli to fluoroquinolones and cephalosporins, but a rising trend in fluoroquinolone-resistant and ESBL-producing strains highlights the need for careful selection of empirical treatments based on patient characteristics.