[Changes in the functional activity of neutrophils during their interaction with Yersinia pestis in vitro].

The functional state and electrochemical properties of human blood neutrophil leukocytes after their in vitro interaction with Y. pestis cells, strain EV, was analyzed. A considerable decrease in the electrophoretic mobility of neutrophil leukocytes and a considerable increase in their phagocytic indices was shown.

[The effect of Yersinia pestis antigens and strains on the level of lymphocyte blast transformation].

Lymphocytic blast-cell transformation (LBCT) is shown to be related both to the genotype of a macroorganism and to the genetically determined expression of individual antigens by the plague microbe. The correlation of LBCT with the level of antiinfectious resistance suggests that this index is of high informative value and that it can be effectively used for testing the cellular immunity and the characteristically biological properties of the plague causative agent and its antigens.

[A gene expression study and the isolation and immunobiological properties of the iron-regulated membrane proteins of the plague microbe].

The study has examined how the plague bacillus expresses genes of two high-molecular weight (190 and 240 kD) iron-regulated membrane proteins (HMWP). The latter were purified and assayed for their immunobiological properties in vitro and in vivo. DNA-probing (at E.

[Changes in the functional activity of oxygen-dependent bactericidal macrophage systems during interaction with Yersinia pestis].

In this work the capacity of Y. pestis, depending on their plasmid composition, for inhibiting the action of the main oxygen-dependent bactericidal systems of macrophages is shown. The data on the modulating influence of Y.