Publications by authors named "M Iu Krylova"
Article Synopsis
- Ketamine, a dissociative anesthetic, alters global consciousness states and brain dynamics, with the study investigating its effects using portable low-density EEG systems instead of traditional methods.
- The study involved 30 male adults in a double-blinded experiment comparing ketamine and saline, analyzing both resting-state and task-driven EEG, finding that ketamine increases redundancy in brain dynamics, especially at alpha frequencies.
- High-order interactions (HOI) revealed that ketamine correlates with dissociative experiences and offers a novel approach to studying brain connectivity and dynamics during drug interventions.
Article Synopsis
- A study involving 30 young adult males utilized a double-blinded crossover design to investigate the effects of racemic ketamine compared to saline infusion on brain dynamics through EEG recordings.
- Ketamine was found to increase redundancy in brain activity, especially in the alpha frequency band, and this effect was more pronounced in a resting state, indicating a shift towards dissociative states of consciousness.
- The study introduces Higher Order Interactions (HOI) as a promising method for analyzing EEG data, highlighting its capability to reveal how different electrode interactions may be associated with experiences like derealization and changes in consciousness due to drug interventions.
Childhood adversity, a prevalent experience, is related to a higher risk for externalizing and internalizing psychopathology. Alterations in the development of cognitive processes, for example in the attention-interference domain may link childhood adversity and psychopathology. Interfering stimuli can vary in their salience, i.
View Article and Find Full Text PDFTemporal neural synchrony disruption can be linked to a variety of symptoms of major depressive disorder (MDD), including mood rigidity and the inability to break the cycle of negative emotion or attention biases. This might imply that altered dynamic neural synchrony may play a role in the persistence and exacerbation of MDD symptoms. Our study aimed to investigate the changes in whole-brain dynamic patterns of the brain functional connectivity and activity related to depression using the hidden Markov model (HMM) on resting-state functional magnetic resonance imaging (rs-fMRI) data.
View Article and Find Full Text PDFEvidence accumulates that oral contraceptive (OC) use modulates various socio-affective behaviors, including empathic abilities. Endogenous and synthetic sex hormones, such as estrogens and progestogens, bind to receptor sites in brain regions (i.e.
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