Investigating the Impact of Sumac Capsules on Postpartum Bleeding among Women at Risk of Bleeding: a three-blind randomized clinical trial.

Objectives: Postpartum hemorrhage is a leading cause of maternal mortality worldwide. Emerging evidence suggests that the sumac plant possesses astringent and anti-inflammatory properties that may help reduce menstrual bleeding. Therefore, this study aimed to determine the effect of sumac capsules on postpartum bleeding among women at risk of excessive bleeding.

Gold/platinum nanorods/temozolomide-UiO-66-NH metal-organic frameworks incorporated to chitosan-grafted polycaprolactone/polycaprolactone core-shell nanofibers for glioblastoma treatment during chemo-photothermal therapy.

The use of biocompatible metal-organic frameworks (MOFs) and electrospun nanofibrous implants shows promise in preventing the recurrence of postsurgical glioblastoma. In this study, temozolomide (TMZ) and platinum‑gold nanorods (PtAu NRs) were encapsulated into the UiO-66-NH MOFs. These were then incorporated into the chitosan-grafted polycaprolactone (PCL) (core)/PCL (shell) nanofibers coated with PtAu NRs for extended release of TMZ during chemo-photothermal therapy against glioblastoma cells.

Improving correlation based super-resolution microscopy images through image fusion by self-supervised deep learning.

Super-resolution imaging is a powerful tool in modern biological research, allowing for the optical observation of subcellular structures with great detail. In this paper, we present a deep learning approach for image fusion of intensity and super-resolution optical fluctuation imaging (SOFI) microscopy images. We construct a network that can successfully combine the advantages of these two imaging methods, producing a fused image with a resolution comparable to that of SOFI and an SNR comparable to that of the intensity image.

Therapeutic Potential of Etrasimod in the Management of Moderately-to-Severely Active Ulcerative Colitis: Evidence to Date.

Etrasimod is a sphingosine 1 phosphate (S1P) receptor modulator approved for the treatment of moderate to severely active ulcerative colitis (UC). Etrasimod selectively activates S1P receptors with no detectable activity on S1P. The ELEVATE clinical trials evaluated the efficacy and safety of etrasimod for UC.

Antimalarial evaluation of selected medicinal plants traditionally used for treatment of fever, by inhibition test of heme polymerization.

Objectives: World Health Organization (WHO) has reported 249 million cases infected by malaria worldwide and 608 thousands deaths in 2022. Investigations for new antimalarial drugs from traditional medicine have proven to be more effective and less expensive. The medicinal plants that have been used for treatment of malaria, generally known as types of fevers in traditional medicine, can be suitable candidates for evaluating antimalarial effects.