Nail toxicity associated with anticancer agents.

In recent decades, cancer mortality rates have declined due to development of systemic antineoplastic agents targeting specific cancer pathways. Nail toxicities associated with these therapies are underrecognized by many and contribute significantly to patient morbidity. Nail changes from chemotherapy occur due to toxicity to continuously dividing nail matrix keratinocytes.

Bioavailability and pharmacokinetics of (poly)phenols following consumption of selected blueberries and a blueberry-rich protein bar by adult males and females: a randomized, crossover, controlled trial.

Background: It is commonly believed that higher nutrient content equates to healthier foods and that food processing lowers nutrient content, although bioavailability studies often indicate otherwise. Blueberries, a rich source of (poly)phenols with proven health benefits, provide a feasible model to evaluate phytochemical bioavailability following consumption of raw and processed fruits.

Objectives: This study evaluates the effect of processing on the bioavailability of (poly)phenols following consumption of 4 interventions: 2 blueberry varieties (i.