Publications by authors named "M Imarai"
Sulfated polysaccharide lambda carrageenan (λ-CGN) was evaluated for its antiviral effect against IPNV using the in vitro infection model of CHSE-214 salmonid cells. A plaque reduction lysis assay revealed that λ-CGN has an IC of 0.9 μg⋅mL, CC > 128 μg⋅mL and a Selectivity Index (SI) > 142.
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- Chemokines are important immune signaling proteins that help direct immune cells to sites of infection, with specific focus on the CXCL9, CXCL10, and CXCL11 chemokines and their receptor CXCR3, which are crucial for T cell and macrophage recruitment.
- This study aims to identify the genes encoding the CXCL9-11/CXCR3 axis in Atlantic salmon, analyze their protein structure, and explore how these genes respond to viral infections and are regulated by gamma interferon.
- Phylogenetic analysis shows that salmon chemokines are evolutionarily distinct from their mammalian counterparts, suggesting different evolutionary pressures, while some salmon chemokine components are induced by viral infections.
Background: As the COVID-19 pandemic persists, infections continue to surge globally. Presently, the most effective strategies to curb the disease and prevent outbreaks involve fostering immunity, promptly identifying positive cases, and ensuring their timely isolation. Notably, there are instances where the SARS-CoV-2 virus remains infectious even after patients have completed their quarantine.
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- The evolution of SARS-CoV-2 variants, particularly the Omicron variant, poses a substantial danger by potentially undermining immunity from vaccinations and previous infections, leading to increased reinfections and localized outbreaks in regions like Chile.
- A study analyzing 578,670 COVID-19 tests from April 2020 to July 2022 found that the highest rates of reinfection in Chile occurred during the fourth and fifth waves, with an average gap of 372 days between infections.
- Despite a significant vaccination rate, the results indicate that the Omicron variant is highly effective at evading immune responses, emphasizing the need for informed public health strategies to address these challenges.
In this study, we investigated the effects of the artificial photoperiods that mimic summer (16L:8D; 16 h Light: 8 h Dark) and winter (8L:16D) solstices, equinoxes (12L:12D), and the artificial 24-h light regimen (24L:0D) on the leukocyte populations and the T helper and regulatory type responses on rainbow trout (Oncorhynchus mykiss). Using flow cytometry analysis, we found that photoperiod induces changes in head kidney leukocyte subsets. The lymphoid subset increased in the 16L:8D summer solstice regime.
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