[Imaging technics in the evaluation of malformations, traumatic and expansive disorders of the orbital region].

In this paper the authors evaluate the usefulness of the new radiological techniques in the study of the orbital region. They describe the role of modern computerized imaging in the planning of their correction of malformative and traumatic diseases of the orbit. Furthermore, the authors evaluate the usefulness of US, CT, and MR imaging in the differential diagnosis of growing masses of the orbit.

MRI in Smith-Lemli-Opitz syndrome type I.

We describe a single case of a polymalformational syndrome in which the MR findings were of great help in the final diagnosis of Smith-Lemli-Opitz syndrome (SLOS) type I. MRI was performed for evaluation of the brain morphology since the clinical and laboratory findings were suggestive but not unequivocally indicative of SLOS. MRI findings of frontal lobe hypoplasia, cortical migration defect, and abnormalities of median line structures prompted the final diagnosis of SLOS.

Bilateral simultaneous cerebellar infarction in the medial branches of the posterior inferior cerebellar artery territories.

We present an unusual case of simultaneous bilateral cerebellar infarction in the territory of the medial and intermediate branches of the posterior inferior cerebellar arteries (mPICA). The patient, a 57-yr-old woman, had no risk factors for cerebrovascular disease but a long-standing hypertension. Pathogenetic hypotheses of this unusual ischemic site of lesion may be referred to: A) two PICAs arising from an occluded basilar artery; B) both medial branches arising from the same PICA on one side; C) a haemodynamic mechanism with hypoperfusion in the most peripheral branches of the arteries; D) a double, simultaneous embolic stroke in mPICAs territory.

High-dose contrast-enhanced MRI in multiple sclerosis.

Contrast-enhanced MRI is effective for assessing disease activity in multiple sclerosis (MS) and may provide an outcome measure for testing the efficacy of treatment in clinical trials. To compare the sensitivity of high-dose gadolinium-HP-DO3A with that of a standard dose of gadolinium-DTPA, we studied 16 patients with relapsing-remitting MS in the acute phase of the disease. Each underwent two MRI examinations within at most 48 h.

[Role of CT and MR in the assessment of lumbar degenerative disk disease].

The application of CT and MR techniques for the evaluation of degenerative disease of lumbar disk is illustrated in this work. A critical review of the literature was done.