Publications by authors named "M Iacovantuono"
Objective: A monocentric cross-sectional study recruiting rheumatoid arthritis (RA) and psoriatic arthritis (PsA) patients residing in the Lazio region, Italy, to assess factors related to diagnostic delay and treatment accessibility.
Methods: Clinical/serological data, including the time between symptom onset, diagnosis, and the beginning of treatment, were collected. Residence, referral to a rheumatologic center, physician who made the diagnosis, and previous misdiagnosis were also evaluated.
Article Synopsis
- The study explores the link between a specific genetic variant (rs11568820) in the vitamin D receptor (VDR) gene and the effectiveness of anti-TNF therapy in patients with rheumatoid arthritis (RA).
- Researchers evaluated 178 Italian RA patients, observing that those carrying the variant allele of the VDR gene had a lower rate of remission after 52 and 104 weeks of treatment.
- The findings indicate that genetic variations in the VDR may influence how well patients respond to anti-TNF drugs, highlighting the importance of personalizing RA treatment based on genetic factors.