[The determination of tetanus antitoxin by the latex agglutination reaction].

A new method to detect the protective value of antitetanic antibody in latex agglutination test (LAT) has been described. The new method is highly sensitive and fast, and requires no special equipment. The optimal conditions of sensibilization, latex types, test providing procedure have been selected.

[The use of the polymerase chain reaction method in studying the causative agents of diphtherial infection].

A method for identification of genomic polymorphism of strains belonging to different biovars Corynebacterium diphtheriae has been described. The method is based on the polymerase chain reaction (PCR) using universal inter-species oligonucleotide primer N 45. Using this method 17 strains of C.

[Mechanism of action of remantadine hydrochloride on Sindbis virus reproduction: inhibition of virus penetration into the cell].

The effect of rimantadine and ammonium chloride on the RNA synthesis of Sindbis virus, added in different times of infection cycle, was studied. When compounds were presented in period of adsorption and first hour post-infection, the maximal inhibitory effect was found. The step blocked by rimantadine was identified as uncoating process (deprotainization).