Publications by authors named "M I Steele"
Purpose: The purpose of this study was to evaluate the correlation between longitudinal monitoring of donor-derived cell free DNA (dd-cfDNA) in lung transplant recipients and a "gold standard" of existing tools (pulmonary function testing, radiographic imaging, laboratory and bronchoscopy data, clinical judgment) to assess allograft function.
Methods: 24 consecutive transplant recipients were prospectively enrolled in this study measuring dd-cfDNA levels monthly in the first year after bilateral lung transplant. Blinded clinical adjudications were performed at the same timepoints to categorize allograft function as stable (FEV1 within 10% of prior value or when compared to best two averaged post-transplant values) or unstable.
Even with the same energy supply, differences in energy sources may affect calf growth and metabolism. In this study, we evaluated the effects of feeding 3 different milk replacers (MR) with different lactose supplies under isoenergetic conditions on calf digestibility, growth, and metabolism-related markers. Fifteen Holstein bull calves were randomly assigned to one of 3 MR feeding treatments: low lactose (L: 38%), medium lactose (M: 41%), or high lactose (H: 46%).
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- Children with autism and other neurodevelopmental concerns often struggle with sensory processing issues and self-regulation difficulties like emotion dysregulation and anxiety, which affects their development.
- This study involved 117 children aged 8-12, aiming to understand the prevalence of self-regulation problems and identify different sensory processing subtypes.
- Findings revealed significant rates of emotion dysregulation (39%), anxiety (19%), and ADHD symptoms (62%), along with five sensory processing subtypes that correlate with various self-regulation challenges, particularly noting distinct patterns among Sensory Over-Responsive and Sensory Seeking groups.
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- Idiopathic pulmonary fibrosis (IPF) is a complex disease, and variations in genetic profiles might influence unique clinical and imaging characteristics.
- Computational image analysis, or radiomics, provides a way to quantify and analyze CT scan features objectively in patients with pulmonary fibrosis.
- The study found that certain genetic variants correlated with deep learning-based classifications of the usual interstitial pneumonia (UIP) pattern on CT, suggesting that advanced imaging analysis could help in understanding genotype-phenotype relationships in lung diseases.
Extrapolating Sentinel Surveillance Information to Estimate National COVID Hospital Admission Rates: A Bayesian Modeling Approach.
Influenza Other Respir Viruses
October 2024
The COVID-19-Associated Hospitalization Surveillance Network (COVID-NET) was established in March 2020 to monitor trends in hospitalizations associated with SARS-CoV-2 infection. COVID-NET is a geographically diverse population-based surveillance system for laboratory-confirmed COVID-19-associated hospitalizations with a combined catchment area covering approximately 10% of the US population. Data collected in COVID-NET includes monthly counts of hospitalizations for persons with confirmed SARS-CoV-2 infection who reside within the defined catchment area.
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