Study of microcirculation in 56 patients with an extremely grave course of food toxoinfections attended by hypovolemic shock and dehydration, stage III-IV, has demonstrated pronounced microcirculatory disorders that manifested in abnormal microvascular tone, diminution of the number of the functioning capillaries, high drop of the blood via the arteriovenous shunts, stagnation of the blood flow and development of metabolic acidosis. Pathogenetic treatment with the polyionic solutions Kvartasol and Trisol in a dose of 70 to 100 ml/kg at a rate of up to 1 ml/kg per minute arrested the microcirculatory disorders and rapidly improved the patients' well-being.
View Article and Find Full Text PDFThe system of hemostasis was subjected to a comprehensive study in 116 adult patients with food toxoinfections of varying severity. The moderate and severe forms were primarily marked by the signs of hypercoagulation and high aggregation of formed elements of the blood. The symptoms of hypocoagulation dominated in extremely severe disease patterns.
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