Oncology professionals' perceptions and recommendations to improve well-being and health at work in times of crisis: qualitative thematic analysis from the ESMO Resilience Task Force survey series.

Background: The European Society for Medical Oncology (ESMO) Resilience Task Force (RTF) was established to address burnout and well-being issues among oncology professionals. In this article, we present findings on shared perceptions and recommendations to support and improve oncology professionals' well-being and health at work.

Materials And Methods: Inductive thematic analysis of qualitative responses from three global ESMO RTF surveys (2020-2021) was conducted using Braun and Clarke's six-step approach.

Harnessing STING Signaling and Natural Killer Cells overcomes PARP Inhibitor Resistance in Homologous Recombination Deficient Breast Cancer.

Homologous recombination deficiency (HRD) contributes to genomic instability and leads to sensitivity to poly ADP-ribose polymerase inhibitors (PARPi). HRD also activates the cyclic GMP-AMP synthase (cGAS)-STimulator of INterferon Genes (STING)-Interferon (IFN) pathway, highlighting the need to understand the impact of cGAS-STING-IFN signaling on PARPi efficacy. In this study, we analyzed a cohort of thirty-five breast cancer (BC) patient-derived xenografts (PDX) and mouse-derived allografts (MDA).

Accounting for unmet needs resulting from cancer-related cognitive impairment.

Purpose: Cancer-related cognitive impairment (CRCI) causes a wide range of unmet needs for cancer survivors. It is unknown which clinical, demographic, cognitive, and psychological factors underpin and account for these various unmet needs. This study aimed to (a) identify factors associated with CRCI-related unmet needs, and (b) establish the most pertinent factors that account for CRCI-related unmet needs.

SPHENISCID ALPHAHERPESVIRUS 1 IN AFRICAN PENGUINS () WITHIN THE SPECIES SURVIVAL PLAN MANAGED POPULATION IN THE US: INCIDENCE AND POPULATION IMPACT.

Spheniscid alphaherpesvirus-1 (SpAHV-1) is associated with respiratory disease in juvenile African penguins (). In 2020, this virus was detected in adult birds with clinical signs of respiratory disease in a previously asymptomatic colony of 21 birds following a recommended introduction of three new birds, including two with a history of herpesvirus as juveniles. Mild to moderate respiratory signs were noted in 33% (8/24) of the colony.

Patients' Experience With Evaluation by Both a Musculoskeletal Physician and Physical Therapist in the Same Digital Visit: Survey Study.

Background: Patients undergoing evaluation for musculoskeletal concerns are often seen by a physician and physical therapist in the in-person setting in a sequential manner. This process typically delays the onset of nonoperative care, inclusive of physical therapy, and creates the risk of inadequate clinical collaboration between physician and physical therapist. To address these issues, we designed a novel initial patient evaluation to a group visit in which both a specialty-trained musculoskeletal physician and physical therapist simultaneously evaluate a patient together in the digital encounter.