New insights into chitosan-Ag nanocomposites synthesis: Physicochemical aspects of formation, structure-bioactivity relationship and mechanism of antioxidant activity.

Herein, a novel approach to the controlled formation of chitosan-Ag nanocomposites (NCs) with different structures and tunable chemical/biological properties was proposed. The chitosan-Ag NCs were obtained using hydrothermal synthesis and varying the concentrations of components. The hypothesis of chitosan-Ag NC synthesis using polysaccharide coils as a "microreactor" system was confirmed.

Hematological and biochemical parameters correlated to hemorheology in Canine Monocytic Ehrlichiosis.

Canine monocytic ehrlichiosis (CME) is an infectious disease that causes hematological changes in dogs. This study investigated the correlations between hematological and hemorheological parameters, serum proteins, and triglycerides in dogs with CME. Fifty-nine blood and/or bone marrow samples were collected from dogs with or without clinical signs of CME.

Zein Nanoparticles-Loaded Flavonoids-Rich Fraction from : Potential Antileishmanial Applications.

Leishmaniasis, caused by protozoa of the genus , is a major global health issue due to the limitations of current treatments, which include low efficacy, high costs, and severe side effects. This study aimed to develop a more effective and less toxic therapy by utilizing zein nanoparticles (ZNPs) in combination with a nonpolar fraction (DCMF) from (Syn. ), a plant rich in dimeric flavonoids called brachydins.

Is Silver a Precious Metal for G-Quadruplex Stabilization Mediated by Porphyrins?

Cancer is a leading cause of death, so continuous efforts into cancer therapy are imperative. In tumor cells, telomerase and oncogene activity are key points for uncontrolled cell growth. Targeting these processes with ligands that inhibit telomerase and/or reduce oncogene expression has been identified as a promising cancer therapy.

Psychometric properties of the reduced version of the Primary Care Assessment Tool (PCATool).

Objective: This cross-sectional study aimed to evaluate the psychometric properties of the reduced version of the Primary Care Assessment Tool (PCATool) for adult patients in the Brazilian National Health Survey 2019, a nationally representative population-based study.

Methods: The reduced version of PCATool-adults measures the presence and extent of the following attributes: degree of affiliation; first-contact access; longitudinality; care coordination; comprehensiveness; family orientation; and community orientation. Exploratory and Confirmatory Factor Analysis were performed.