Effects of Phytochemicals on Metabolic Diseases and Human Health.

Metabolic diseases constitute a worldwide health concern because of their increasing prevalence and associated mortality [...

Identification of Potential Sepsis Therapeutic Drugs Using a Zebrafish Rapid Screening Approach.

In the military, combat wound infections can progress rapidly to life-threatening sepsis. The discovery of effective small-molecule drugs to prevent and/or treat sepsis is a priority. To identify potential sepsis drug candidates, we used an optimized larval zebrafish model of endotoxicity/sepsis to screen commercial libraries of drugs approved by the U.

Treatment of Inpatient Opioid Withdrawal with Short-Acting Full Agonist Opioids at a Safety-Net Hospital.

Background: Fentanyl use leads to increased opioid tolerance in people with opioid use disorder, complicating management of opioid withdrawal syndrome. While accepted as gold standard, methadone and buprenorphine may be insufficient to treat acute opioid withdrawal. Short-acting full agonist opioids (SAFAO) may improve treatment in the acute care setting.

Preschool and Me: Educational-clinical linkage to improve health equity for children with developmental delays and disabilities from historically marginalized communities.

Societal and structural inequities have resulted in longstanding health care disparities among Black, Latino/a/e, and low-income preschool children with developmental delays and disabilities (PCw/DD), depriving them of educational and therapeutic services that improve future academic, economic, and health outcomes. To address this issue, we developed Preschool and Me (PreM), a community-clinical linkage (CCL) implemented within healthcare settings serving historically marginalized communities. This novel CCL, an educational-medical linkage model, aims to increase access to school-based services for PCw/DD.

'Good morning Metro shoppers!' Food insecurity, COVID-19 and the emergence of roll-call neoliberalism.

From April 2020 to December 2021, the Canadian federal government earmarked $330,000,000 through the Emergency Food Security Fund to address food insecurity during the COVID-19 global pandemic. These funds were disbursed through a handful of national and regional emergency food and food justice agencies to smaller front-line organizations for the purchase of emergency food provisions and personal protective equipment, and to hire additional workers. We theorize these dynamics within the broader processes of neoliberalization and argue that the Canadian federal government was conscripting food justice and community development organizations into its efforts to address dramatically increasing rates of food insecurity across the country through charity emergency food provisioning.