Publications by authors named "M I Katsidoniotaki"
Background: Preeclampsia is associated with autonomic dysregulation during pregnancy; however, less is known about autonomic function in the first week postpartum after preeclampsia.
Methods: We retrospectively analyzed data from a prospective cohort of women with and without preeclampsia. Continuous blood pressure and heart rate were measured with finger plethysmography within 7 days postpartum.
Article Synopsis
- The study investigates how changes in dynamic cerebral autoregulation (DCA) affect mothers after experiencing severe preeclampsia postpartum, compared to healthy postpartum and non-pregnant women.
- Researchers used techniques like transcranial Doppler and blood pressure monitoring to measure DCA parameters within a week of delivery in these groups.
- Results indicated that postpartum participants showed faster autoregulatory responses but with impaired dampening effects, suggesting a hyperdynamic state in DCA regardless of preeclampsia status.
A data-driven technique for parsimonious modeling and analysis of dynamic cerebral autoregulation (DCA) is developed based on the concept of diffusion maps. Specifically, first, a state-space description of DCA dynamics is considered based on arterial blood pressure, cerebral blood flow velocity, and their time derivatives. Next, an eigenvalue analysis of the Markov matrix of a random walk on a graph over the dataset domain yields a low-dimensional representation of the intrinsic dynamics.
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