Bilateral Carotid Artery Molecular Calcification Assessed by [F] Fluoride PET/CT: Correlation with Cardiovascular and Thromboembolic Risk Factors.

Atherosclerosis, a leading cause of mortality and morbidity worldwide, involves inflammatory processes that result in plaque formation and calcification. The early detection of the molecular changes underlying these processes is crucial for effective disease management. This study utilized positron emission tomography/computed tomography (PET/CT) with [F] sodium fluoride (NaF) as a tracer to visualize active calcification and inflammation at the molecular level.

[Synthesis of a 17-member peptide (143-159)--the VP(1) protein fragment of A(12) foot-and-mouth disease virus. II. Condensation of fragments].

A 17-membered peptide corresponding to the amino acid sequence of (143-159) site of protein VP1 of A12 foot-and-mouth disease virus has been obtained by mixed anhydride method condensations of the earlier synthesized fragments. A norleucine residue has been attached, as a label, to the ends of peptides obtained. The complete deprotection was performed by hydrogenation peptides' hydrochlorides and the products were purified by HPLC.