[Morphofunctional evaluation of the results of reconstructive operations of gastroenteroanastomosis in peptic ulcer].

The mucosa of the gastric stump, abducting and adducting loops of small intestine in patients with peptic ulcers of gastrointestinal anastomosis has been examined with scanning, transmission electron and light microscopy, morphometry, and the study of secretion at various periods after reconstructive surgery combined with vagotomy. An increase of the number of chief and parietal cells in the gastric stump fundal glands, increase of the thickness of the mucosa due to the deepening of the crypts of the adducting and abducting loops of the small intestine, and alteration of the mucosal microrelief of the gastric stump and small intestine are noted in peptic ulcers of gastrointestinal anastomosis especially near the site of anastomosis. This is accompanied by an increase of mucosal secretory activity.

[Changes in the gastric mucosa in complicated forms of peptic ulcer and postgastrectomy syndromes].

Complex studies of the secretory function of the stomach have shown its activity to depend upon the type of gastric ulceration. It allows gastric ulcers to be differentiated into those with hyposecretory (primary ulcers) and hypersecretory (associated and secondary ulcers) syndromes. High secretory activity of the stomach with duodenal ulcers is confirmed by the results of morphological investigations.

[Morphofunctional state of the gastric mucosa in primary, combined and secondary stomach ulcer].

The morphofunctional condition of the gastric mucosa was studied in primary, combined, and secondary peptic ulcers. The secretory function of the stomach in primary ulcers was found not to differ from that in normal subjects. An increase in the number of all kinds of epithelial cells of fossi and glands of the fundal part was observed, the percentage ratio of the cells not changing significantly.