Publications by authors named "M I Garcia-Garcia"
Outcomes of Surgical Treatment of Peri-Implantitis: A Retrospective Cohort Study.
Int J Oral Maxillofac Implants
January 2025
Purpose: The available scientific evidence on the effectiveness of the surgical treatment of peri-implantitis is limited. The aim of this study was to assess the risk of recurrence or disease progression in patients with peri-implantitis that underwent surgical treatment.
Materials And Methods: A retrospective cohort study was carried out in patients subjected to peri-implant surgery between 2015 and 2021, and with a minimum follow-up of 12 months.
Breast cancer poses a global threat with rising incidence and high mortality. Conventional treatments, including chemotherapy, radiation, surgery, and immunotherapy, have side effects, such as resistance issues and adverse effects due to genetic mutations. Meanwhile, noble metal nanoparticles (NPs) synthesized using environmentally friendly methods offer alternative treatments.
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- Glypican-3 (GPC3) is a potential target for T-cell therapy in hepatocellular carcinoma (HCC), but current CAR T-cell approaches face issues like low persistence and GPC3 shedding.
- Researchers immunized HLA-A2 transgenic mice to find GPC3-specific T-cell receptors (TCRs) and engineered human T cells (TCR-Ts) that effectively recognize GPC3-positive HCC cells.
- TCR-B-T cells showed superior effectiveness compared to traditional CAR T-cells, and combining CAR-T and TCR-B-T cells may enhance therapeutic results in treating HCC.
The mechanics of the extracellular matrix (ECM) determine cell activity and fate through mechanoresponsive proteins including Yes-associated protein 1 (YAP). Rigidity and viscous relaxation have emerged as the main mechanical properties of the ECM steering cell behavior. However, how cells integrate coexisting ECM rigidity and viscosity cues remains poorly understood, particularly in the high-stiffness regime.
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