Environmental and biological measurements of the anesthetic isoflurane and its possible toxic effects in veterinarians.

We evaluated both environmental (workplace) and biological (urine) exposure to the anesthetic isoflurane concerning the effects of such exposure on the hematological, hepatic, and renal parameters in veterinarians. Samples were collected from exposed and nonexposed (volunteers) groups to assess hematological and several biochemical markers, and isoflurane was measured in the workplace air and veterinarian's urine. Isoflurane was detected at high levels in the air and urine.

Evaluation of the potential of phage phSE-5 to fight Salmonella typhimurium in milk, liquid whole egg and eggshell.

Aims: This study aimed to evaluate the potential of phage phSE-5 to inactivate Salmonella enterica serovar Typhimurium in milk (at 4, 10 and 25°C), liquid whole egg and eggshell (at 25°C for both matrices).

Methods And Results: Since the success of phage treatment in food depends on maintaining phage viability towards different food conditions, firstly the stability of phage phSE-5 at different temperatures and pHs was assessed. The effect of phage phSE-5 against S.

From indoors to outdoors: Impact of waste anesthetic gases on occupationally exposed professionals and related environmental hazards - A narrative review and update.

Waste anesthetic gases (WAGs) are trace-concentration inhaled anesthetics that exist worldwide because they are released into the ambient air of operating rooms (ORs) and post-anesthesia care units. WAGs cause indoor contamination, especially in ORs lacking proper scavenging systems, and occupational exposure, while promoting climate change through greenhouse gas/ozone-depleting effects. Despite these controversial features, WAGs continue to pose occupational health hazards.

Genetic instability of a single exposure to sevoflurane at different concentrations in monitored mice.

Sevoflurane is an inhalation anesthetic widely used for general anesthesia, but its genotoxic potential is controversial in clinical studies. It is unknown whether the effects are due to surgery or the anesthetic. Thus, for the first time, the present study investigated genotoxicity in peripheral blood cells and in target organs (liver, lung, and kidney) and micronucleus (MN) in the bone marrow of a single exposure to sevoflurane at three different concentrations in monitored mice.

Eighteen-year trends in the rates of intra-operative cardiac arrest and associated mortality at a public university hospital in Brazil.

Background: Intra-operative cardiac arrest is a rare but life-threatening event. Over the past two decades, various initiatives have improved the care of patients undergoing surgery at our quaternary teaching hospital in Brazil. We aimed to evaluate the epidemiology of intra-operative cardiac arrest and associated 30-day mortality over an 18-year period.