Publications by authors named "M I Bogachev"
Article Synopsis
- Plant extracts, particularly from hops, show strong antimicrobial activity against Staphylococcus aureus strains, effective in both free-floating and biofilm forms, making them viable for oral care.
- The hop extract worked as well as standard antibiotics (amikacin, ciprofloxacin, and ceftriaxone) and exhibited synergy, enhancing the effectiveness of these antibiotics against various bacterial isolates.
- Chemical analysis of the extract identified key compounds (prenylated flavonoids and acylphloroglucides) that contribute to its antimicrobial effects and ability to reduce the minimum inhibitory concentration (MIC) of antibiotics, suggesting its potential as both an antiseptic and a complement to conventional treatments.
In the last decade, Ficin, a proteolytic enzyme extracted from the latex sap of the wild fig tree, has been widely investigated as a promising tool for the treatment of microbial biofilms, wound healing, and oral care. Here we report the antibiofilm properties of the enzyme immobilized on soluble carboxymethyl chitosan (CMCh) and CMCh itself. Ficin was immobilized on CMCh with molecular weights of either 200, 350 or 600 kDa.
View Article and Find Full Text PDFIn a changing climate, forest ecosystems have become increasingly vulnerable to continuously exacerbating heat and associated drought conditions. Climate stress resilience is governed by a complex interplay of global, regional, and local factors, with hydrological conditions being among the key players. We studied a Scots pine ( L.
View Article and Find Full Text PDFSmall heat shock proteins (sHSPs) represent a first line of stress defense in many bacteria. The primary function of these molecular chaperones involves preventing irreversible protein denaturation and aggregation. In , fibrillar IbpA binds unfolded proteins and keeps them in a folding-competent state.
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