Publications by authors named "M I Balea"
Background: Ischemic stroke (IS) often leads to cognitive and motor impairments. This study aimed to investigate whether Memory-Guided Saccade Tasks (MGSTs) could be used to assess cognitive function in stroke patients.
Methods: A secondary data analysis was conducted on 62 individuals with supratentorial IS.
Background: Since the beginning of the COVID-19 pandemic, empiric antibiotics (ATBs) have been prescribed on a large scale in both in- and outpatients. We aimed to assess the impact of antibiotic treatment on the outcomes of hospitalised patients with moderate and severe coronavirus disease 2019 (COVID-19).
Methods: We conducted a prospective multicentre cohort study in six clinical hospitals, between January 2021 and May 2021.
Background: N-Pep-12 is a dietary supplement with neuroprotective and pro-cognitive effects, as shown in experimental models and clinical studies on patients after ischemic stroke. We tested the hypothesis that N-Pep-12 influences quantitative electroencephalography (QEEG) parameters in patients with subacute to chronic supratentorial ischemic lesions.
Methods: We performed secondary data analysis on an exploratory clinical trial (ISRCTN10702895), assessing the efficacy and safety of 90 days of once-daily treatment with 90 mg N-Pep-12 on neurocognitive function and neurorecovery outcome in patients with post-stroke cognitive impairment against a control group.
Cognition is the most complex function of the brain. When exploring the inner workings of cognitive processes, it is crucial to understand the complexity of the brain's dynamics. This paper aims to describe the integrated framework of the cognitive function, seen as the result of organization and interactions between several systems and subsystems.
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- The study aimed to investigate the effects of N-Pep-12 supplementation on cognitive recovery in middle-aged and older adults who experienced an ischemic stroke.
- It was a randomized-controlled clinical trial that evaluated the safety and efficacy of a daily 90 mg dose of N-Pep-12 over 90 days compared to a control group.
- Results showed significant improvements in cognitive measures like the Montreal Cognitive Assessment and anxiety levels, suggesting that N-Pep-12 may benefit neurorecovery after stroke.