Interdisciplinary rehabilitation for the transition out of homelessness with a traumatic brain injury.

People experiencing homelessness (PEH) face higher rates of traumatic brain injury (TBI), which is associated with greater unmet healthcare and social needs and increased difficulty transitioning out of homelessness. While efforts have emerged to address this TBI disparity via screening, staff training and case management, gaps exist in the delivery of evidence-based TBI rehabilitation to PEH. This case report describes the delivery of interdisciplinary TBI rehabilitation to a male patient experiencing homelessness within a US context.

Decoy-resistant IL-18 reshapes the tumor microenvironment and enhances rejection by anti-CTLA-4 in renal cell carcinoma.

The cytokine interleukin-18 (IL-18) has immunostimulatory effects but is negatively regulated by a secreted binding protein, IL-18BP, that limits IL-18's anti-cancer efficacy. A "decoy-resistant" form of IL-18 (DR-18), that avoids sequestration by IL-18BP while maintaining its immunostimulatory potential, has recently been developed. Here, we investigated the therapeutic potential of DR-18 in renal cell carcinoma (RCC).

Sorafenib or anthracycline-based chemotherapy for progressive desmoid tumors.

Background: Desmoid tumors can cause morbidity due to local invasion, potentially being fatal when fast growth compromises vital structures. In this context, a timely treatment response is required. This study aims to compare the activity of sorafenib and anthracycline-containing regimens during the first year of treatment.

Intersectionality and Social Drivers of Health in Cardiovascular Care.

Social drivers of health (SDOH) are a significant contributor to persistent cardiovascular health disparities in the United States and globally. SDOH include psychosocial, environmental, socioeconomic, cultural, and governmental factors that impact health behaviors and outcomes. Multiple social drivers have been associated with trends in cardiovascular disease risk and health outcomes.