Publications by authors named "M Huptych"

Background: In refractory cardiac arrest, extracorporeal cardiopulmonary resuscitation may increase the survival chance. However, in cases of unsuccessful treatment, extracorporeal cardiopulmonary resuscitation may additionally provide an important source of organ donors. Therefore, we hypothesized that implementing extracorporeal cardiopulmonary resuscitation service into a high-volume cardiac arrest center's routine would increases organ donors' availability.

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Background: It is unclear how invasive resuscitative protocols may impact the time-dependent prognosis of out-of-hospital cardiac arrest (OHCA) resuscitations, or the relationship between intra-arrest transport and outcomes.

Methods: We performed a secondary analysis of the Prague OHCA Study, which randomized refractory OHCAs to "invasive" (intra-arrest transport for possible ECPR initiation) vs. "standard" resuscitation strategies (predominantly performed on-scene).

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, group A streptococci (GAS) bacteriaemia, is a life-threatening infection with high mortality, requiring fast diagnosis together with the use of appropriate antibiotic therapy as soon as possible. Our study analysed data from 93 patients with GAS bacteraemia at the General University Hospital in Prague between January 2006 and March 2024. In the years 2016-2019 there was an increase in GAS bacteraemia.

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Article Synopsis
  • The study aimed to evaluate the long-term outcomes of extracorporeal cardiopulmonary resuscitation (ECPR) compared to conventional CPR (CCPR) in patients with refractory out-of-hospital cardiac arrest (OHCA).
  • A total of 256 patients were randomly assigned to either ECPR or CCPR during resuscitation, with a long-term follow-up conducted 5.3 years later.
  • Results showed that 27.6% of the ECPR group survived compared to 19.7% in the CCPR group, indicating improved long-term survival with ECPR, although neurological outcomes and quality of life were similar for both groups.
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Background: The impact of serial imaging on the outcome of ICU patients has not been studied specifically in patients with high illness severity.

Methods: The authors sought a relationship between the numbers of antero-posterior supine chest X-rays (CXR), computed tomography (CT) examinations, and outcome in a cohort of 292 patients with severe COVID-19 ARDS collected over 24 months in a high-volume ECMO center with established ultrasound and echocardiographic diagnostics. Of the patients, 172 (59%) were obese or morbidly obese, and 119 (41%) were treated with ECMO.

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