Publications by authors named "M Hunter Land"

El Paso Health Education and Awareness Team (EP-HEAT®) is a bilingual program focused on increasing health awareness and dispelling health-related misinformation in the U.S.-Mexico border region.

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Background: Research suggests that marginalized young adults, particularly sexual and gender minorities (SGM), face distinctive healthcare transition challenges. SGM often navigate a complex intersection of identities, experiences, and stressors that can contribute to mental health disparities. However, they often lack access to appropriate support and resources tailored to their needs, which can result in increased psychological distress.

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Background: The relationship between thrombosis and cancer is based on evidence that cancer promotes prothrombotic changes in the host hemostatic system. The activation of blood coagulation is closely linked to tumor growth and dissemination.

Aims: To evaluate whether quantifications of plasma circulation tumor deoxyribonucleic acid (DNA) and thrombin-antithrombin complex could act as predictors for thrombotic events and death in patients with gastric or colorectal adenocarcinomas, while also evaluating the Karnofsky Performance Status.

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Article Synopsis
  • Recent advancements in genetic manipulation have made it possible to create specific deletions in mitochondrial DNA (mtDNA) in human cells, which can help study diseases linked to these genetic changes.
  • A method involving co-expression of end-joining machinery and targeted endonucleases was developed, showcasing effectiveness by generating clonal cell lines with a significant mtDNA deletion and varying levels of heteroplasmy.
  • Research showed that when mtDNA deletion reached around 75%, it led to severe cellular dysfunction and identified distinct nuclear gene expression changes in response to mtDNA deletions, suggesting insights for potential therapies.
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