Publications by authors named "M Hunault"
Background And Aims: Primary lung tumors (PLTs) in children are rare, and surgery remains the key to ensure remission. Here we describe the PLTs clinical characteristics, their management, and the pulmonary outcome following surgery.
Methods: We carried out a French national cohort of pediatric PLTs from 2013 to 2023 from the FRACTURE rare pediatric tumors national database.
Article Synopsis
- Despite initial treatment with midostaurin (MIDO) and chemotherapy in FLT3-mutated acute myeloid leukemia (AML), many patients face relapses, with complete remission rates around 60-70% and over 40% relapsing.
- A study of 150 patients with refractory/relapsed (R/R) AML revealed that those treated with MIDO showed lower persistence of FLT3-ITD mutations compared to those who did not receive MIDO (68% vs. 87.5%).
- The study found that detecting multiple FLT3-ITD clones at diagnosis related to a higher persistence rate of these mutations at relapse, indicating the need for sensitive techniques in FLT3-
Uranium-plutonium mixed oxides, containing few mol % of Am, are currently studied as fuel for Sodium Fast Reactors. The study of the O/M ratio of these fuels is of main interest, as its variation can induce issues for reactor safety. For this purpose, four UPuAmO samples (0.
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- A new community of heads of haematology departments has been formed to provide mutual support in response to challenges within the French hospital system.
- An inaugural seminar held in January 2023 laid the groundwork for this initiative, fostering connections and collaboration among participants.
- The community expanded in January 2024, involving a wider group of department heads, enhancing teamwork and resource-sharing to improve hospital management and operations.
Understanding the nature of metal-ligand bonding is a major challenge in actinide chemistry. We present a new experimental strategy for addressing this challenge using actinide 34 resonant inelastic X-ray scattering (RIXS). Through a systematic study of uranium(IV) halide complexes, [UX], where X = F, Cl, or Br, we identify RIXS spectral satellites with relative energies and intensities that relate to the extent of uranium-ligand bond covalency.
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