Publications by authors named "M Huerta"

Background: Circulating tumor DNA (ctDNA) analysis has emerged as a minimally invasive tool for detecting minimal residual disease (MRD) in colorectal cancer (CRC) patients. This enables dynamic risk stratification, earlier recurrence detection, and optimized post-surgical treatment. Two primary methodologies have been developed for ctDNA-based MRD detection: tumor-informed strategies, which identify tumor-specific mutations through initial tissue sequencing to guide ctDNA monitoring, and tumor-agnostic approaches, which utilize predefined panels to detect common cancer-associated genomic or epigenomic alterations directly from plasma without prior tissue analysis.

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  • * The review aimed to evaluate discharge opioid prescribing practices for neurosurgical patients and assess whether neurosurgeons are over-prescribing opioids, as existing literature on this topic is limited.
  • * A systematic review identified 23 relevant studies, revealing a mix of over-prescribing and under-prescribing of opioids, highlighting a need for individualized patient care and better quality research to help establish effective prescribing guidelines.
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  • This study assessed the impact of particulate matter (PM) pollution on cardiovascular disease (CVD) in Latin American and Caribbean countries, highlighting the significant health burden associated with PM exposure.
  • It found that in 2021, PM pollution accounted for about 2.97 million disability-adjusted life years (DALYs) related to CVD, with greater effects in lower socio-demographic index (SDI) regions such as Haiti, Honduras, and Guatemala.
  • The results emphasize the need for public health strategies focused on decreasing PM pollution to help vulnerable populations and improve overall health outcomes in these areas.
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This study aimed to evaluate the pneumonia risk based on the patient's sex during the COVID-19 pandemic and the early months of the endemic phase of the disease in Mexico. A retrospective cohort study was conducted using a dataset resulting from the epidemiological surveillance of COVID-19 (February 2020 to August 2023). Data from 1.

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Cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus (CsCE) can epimerize and isomerize lactose into epilactose and lactulose respectively. Competition between these reactions reactions has prompted the search for new enzymes to drive the reaction in one direction or the other. The isomerization and epimerization capacity of a novel mutant CsCE (CsCE H356N) was evaluated, obtaining a maximum lactulose yield of 64.

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