History of surgical treatment of lymphatic drainage at the Department of Plastic and Aesthetic Surgery, St. Anne's University Hospital in Brno.

The Department of Plastic and Aesthetic Surgery, St. Anne's University Hospital in Brno, and Faculty of Medicine of Masaryk University, Brno, has a long history of surgical treatment of lymphedema and elephantiasis, which started in 1970s. There were many types of surgeries described and performed at our department - starting with prof.

SURGICAL CORRECTION OF LABIA MINORA HYPERTROPHY, A PERSONAL TECHNIQUE.

Background: Labia minora hypertrophy is a congenital or acquired condition in which both labia minora (or more rarely only one) protrude beyond the edge of the labia majora. The authors present a surgical technique of volumetric reduction of hypertrophic labia minora, associated with lipofilling of the labia majora.

Methods: Between 2005 and 2014, 27 patients underwent surgical reduction of labia minora, as described by Altier and Rouzier.

Propeller flap for treatment of a poststernotomy sternal fistula: a case report.

Unlabelled: The treatment of post-operative deep sternal wound infections is a real challenge for surgeons. Conservative treatment with debridement and vacuum-assisted closure (VAC) therapy is not always successful. In the most severe and chronic cases, a surgical debridement and reconstruction of the defect is mandatory.

Increased liver oxidative stress and altered PUFA metabolism precede development of non-alcoholic steatohepatitis in SREBP-1a transgenic spontaneously hypertensive rats with genetic predisposition to hepatic steatosis.

The temporal relationship of hepatic steatosis and changes in liver oxidative stress and fatty acid (FA) composition to the development of non-alcoholic steatohepatitis (NASH) remain to be clearly defined. Recently, we developed an experimental model of hepatic steatosis and NASH, the transgenic spontaneously hypertensive rat (SHR) that overexpresses a dominant positive form of the human SREBP-1a isoform in the liver. These rats are genetically predisposed to hepatic steatosis at a young age that ultimately progresses to NASH in older animals.

Relationship between insulin resistance and muscle triglyceride content in nonobese and obese experimental models of insulin resistance syndrome.

In nonobese hereditary hypertriglyceridemic (HTg) rats and obese HTg Koletsky SHROB/Kol rats, muscle triglyceride accumulation and its relationship to glucose homeostasis and tissue sensitivity to insulin action were examined. Soleus muscle and diaphragm triglyceride contents were markedly increased in HTg rats as compared with controls and were further increased in obese animals. On the other hand, glucose intolerance and impairment of insulin-stimulated in vitro glycogen synthesis were of a similar degree in nonobese as well as obese animals.