Publications by authors named "M Hosaka"

Background: Paraspinal muscle abscesses are rare, and generally occur due to injections or hematogenous dissemination. Here, we describe a rare case of a paraspinal muscle and the ipsilateral psoas major abscess in the lumbar region that communicated via the interspaces of the costal processes.

Case Report: An 83-year-old man with poorly controlled diabetes mellitus and no history of puncture complained of right low back pain for the past 2 months.

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SummaryPrevious studies have suggested that chromogranin A (CgA) is a partner molecule of secretogranin III (SgIII). In mouse pituitary corticotroph-derived AtT-20 cells, SgIII plays a role in sorting CgA/hormone aggregates into secretory granules (SGs). Although CgA expression is equivocal, CgB is clearly detectable in the rat pituitary corticotrophs.

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Substances released outside of the cells during cell necrosis are collectively called danger-associated molecular patterns (DAMPS) or alarmins. A pro-inflammatory cytokine, interleukin-1α (IL-1α) is known as a typical alarmin. IL-1α transmits signals by binding to IL-1 receptor 1 (IL-1R1), type I protein, expressed on the cell membrane of target cells, but detection of IL-1R1 at the protein and mRNA levels is difficult.

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Article Synopsis
  • Clinical amyopathic dermatomyositis is a skin condition that lacks muscle symptoms and is often associated with anti-melanoma differentiation-associated gene 5 antibodies, particularly in Japanese patients, leading to poor outcomes in those with lung complications.
  • A 52-year-old male presented with severe respiratory issues and skin rashes, diagnosed with dermatomyositis-related interstitial pneumonia, but treatment with steroids and immunosuppressants was largely ineffective.
  • Despite some initial improvement after switching medications, the patient ultimately faced worsening respiratory failure due to invasive pulmonary aspergillosis, resulting in a fatal outcome.
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Article Synopsis
  • Delayed eruption of permanent teeth is common, but impaction of the mandibular first molar is rare, often caused by issues like odontogenic cysts and tumors.
  • The article details two cases where odontogenic tumors led to the delayed eruption of the mandibular first molar in children, with specific diagnoses of ameloblastic fibro-odontoma and odontoma.
  • Treatment involved curettage of the tumors and fenestration of the impacted molars, which resulted in the successful eruption of the first molar in both cases.
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