The association of erythromycin ethylsuccinate with acute colitis in horses in Sweden.

In Sweden there are several reports of mares developing acute colitis while their foals were being treated orally for Rhodococcus equi pneumonia with the combination of erythromycin and rifampicin. In this study 6 adult horses were given low oral dosages of these antibiotics, singly or in combination. Within 3 days post administration of erythromycin, in one case in combination with rifampicin, 2 horses developed severe colitis (one fatal).

Effect of procaine benzylpenicillin alone or in combination with dihydrostreptomycin on udder pathogens in vitro and in experimentally infected bovine udders.

Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of benzylpenicillin (PEN) and dihydrostreptomycinsulfate (DHS) were determined for freshly isolated bovine udder pathogens. Killing curves were determined to study synergism of PEN and DHS on Staphylococcus aureus and Streptococcus uberis. Healthy udder quarters of cows in their first lactation were inoculated with Str dysgalactiae or Str uberis strains.