Publications by authors named "M Holody"

Rationale And Objectives: The aim of this study was to evaluate the feasibility of partnering with engineering students and critically examining the merit of the problem identification and analyses students generated in identifying sources impeding effective turnaround in a large university department of diagnostic radiology. Turnaround involves the time and activities beginning when a patient enters the magnetic resonance scanner room until the patient leaves, minus the time the scanner is conducting the protocol.

Materials And Methods: A prospective observational study was conducted, in which four senior undergraduate industrial and operations engineering students interviewed magnetic resonance staff members and observed all shifts.

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Boronic acid based anthracene dyes were designed, synthesized, and immobilized to solid phase, creating a continuous glucose sensor. Glucose sensitivities of dyes can decrease drastically after immobilization, therefore how to immobilize a dye to solid phase without changing the dye property is a key issue in developing the sensor. The glucose sensitivity of the simplest 1st generation sensor, which is based on an immobilized mono-phenylboronate/single-arm type, came short of the sensitivity requirement for practical use, because of the very moderate fluorescence intensity change over the physiological glucose range.

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We examined the performance characteristics of a new bedside blood gas monitor. This monitor's fluorescent pH, PCO2, and PO2 sensors are embedded in a cassette, which is calibrated in vitro and then inserted into the patient's radial artery tubing set. In 50 medical ICU patients, 683 paired monitor and conventional blood gas analyzer values were obtained.

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Article Synopsis
  • A new bedside monitor (CDI 2000) has been developed for real-time blood gas measurements, allowing blood to be drawn and returned with minimal loss and infection risk.
  • In vitro tests using bovine blood showed the monitor had very small measurement biases, indicating high accuracy compared to traditional methods.
  • Trials in normal volunteers also demonstrated the monitor's performance is on par with established blood gas analyzers, suggesting it could be a reliable alternative in clinical settings.
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