Publications by authors named "M Holierook"

Article Synopsis
  • International guidelines recommend assessing frailty before Transcatheter Aortic Valve Implantation (TAVI), but there's no standard method to do so; this study used the Edmonton Frail Scale (EFS) to evaluate frailty status in patients.
  • In a study of 357 TAVI patients, higher EFS scores (indicating greater frailty) were linked to longer hospital stays and increased mortality rates within 30 days to 4 years post-procedure.
  • The findings suggest that the EFS is an effective tool for identifying frailty in TAVI patients and could guide clinical decisions to improve patient outcomes and reduce the risk of complications.
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Article Synopsis
  • - The study aimed to evaluate whether low-dose dobutamine stress echocardiography (DSE) can predict residual mitral regurgitation (MR) after transcatheter edge-to-edge mitral valve repair (TMVR) procedures.
  • - Findings showed that among 39 patients, those who experienced an increase in MR during DSE were more likely to have significant residual MR at discharge, highlighting DSE's predictive value.
  • - The high sensitivity (100%) and specificity (85%) of DSE make it a powerful tool for guiding clinical decisions post-TMVR, potentially leading to better patient outcomes.
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Background: Symptomatic tricuspid regurgitation (TR) is increasingly prevalent and impairs quality of life and survival, despite medical treatment. Transcatheter tricuspid valve repair (TTVR) has recently become available as a treatment option for patients not eligible for tricuspid valve surgery. In this study we describe the early experience with TTVR in the Netherlands.

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Objectives: The aim of this study was to determine the course of tricuspid regurgitation (TR) after transcatheter mitral valve repair (TMVR), identify predictors for severe TR after TMVR and determine the association of severe TR after TMVR with outcome.

Background: TR is often present in patients with symptomatic mitral regurgitation (MR) and is associated with increased morbidity and mortality. The clinical course of TR after TMVR has not been clearly determined.

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The current coronavirus disease 2019 (COVID-19) crisis has led to a relative unavailability of anaesthesiological support for non-acute cardiac care. Currently, transfemoral transcatheter aortic valve implantation (TF-TAVI) is predominantly performed as an elective catheterisation laboratory (cath lab) procedure. Hence, the performance of TAVI could come to a halt amidst the COVID-19 crisis.

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