Publications by authors named "M Hiroi"
Article Synopsis
- Xanthogranulomatous appendicitis (XGA) is a rare inflammatory condition of the appendix that can mimic cancer on imaging, making diagnosis challenging.
- A 78-year-old woman with a history of cholangiocarcinoma presented with an irregular pelvic mass but showed no symptoms of appendicitis; despite fears of cancer recurrence, she was ultimately diagnosed with XGA through surgery.
- This case highlights the difficulty in preoperatively diagnosing XGA, as it can present without typical symptoms or clear imaging indicators, often leading to confusion with malignancy.
Article Synopsis
- * A case study highlighted a 67-year-old man with unresectable GC and splenic metastasis, who was treated with anticoagulation and chemotherapy, leading to tumor shrinkage.
- * After successful chemotherapy, the patient underwent a laparoscopic total gastrectomy and distal pancreaticosplenectomy, recovering well and remaining recurrence-free six months post-surgery.
While sleeping, many vertebrate groups alternate between at least two sleep stages: rapid eye movement and slow wave sleep, in part characterized by wake-like and synchronous brain activity, respectively. Here we delineate neural and behavioural correlates of two stages of sleep in octopuses, marine invertebrates that evolutionarily diverged from vertebrates roughly 550 million years ago (ref. ) and have independently evolved large brains and behavioural sophistication.
View Article and Find Full Text PDFChemokines are a group of cytokines involved in the mobilization of leukocytes, which play a role in host defense and a variety of pathological conditions, including cancer. Interferon (IFN)-inducible chemokines C-X-C motif ligand 9 (CXCL), CXCL10, and CXCL11 are anti-tumor chemokines; however, the differential anti-tumor effects of IFN-inducible chemokines are not completely understood. In this study, we investigated the anti-tumor effects of IFN-inducible chemokines by transferring chemokine expression vectors into a mouse squamous cell carcinoma cell line, SCCVII, to generate a cell line stably expressing chemokines and transplanted it into nude mice.
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