Ciguatera poisoning (CP), caused by ciguatoxins (CTXs), is one of the most common food-borne diseases, affecting more than 50,000 people each year. In most cases, CP are managed with symptomatic and supportive remedies, and no specific treatment has been devised. In this study, toward the development of therapeutic antibodies for CP, we examined to humanize mouse anti-CTX3C antibody 10C9 (m10C9), which exhibited neutralizing activity against ciguatoxin in vitro and in vivo.
View Article and Find Full Text PDFBackground: Factors related to surgical outcomes of type I tympanoplasty for tympanic membrane (TM) perforation in children are controversial.
Objectives: To investigate factors related to anatomical results of type I tympanoplasty for TM perforation 1 year after surgery.
Material And Methods: We examined 68 ears.
Proc Jpn Acad Ser B Phys Biol Sci
November 2023
Rikō Majima published seven papers in this journal, and seeing these papers and their surrounding contexts allows us to glance at the birth of a galaxy of scientists.
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