The more random people's preference judgments are, the more they explore in gambling tasks.

Background: The decision-making process has been investigated separately in the context of externally guided decision-making (EDM, e.g., a gambling task) and internally guided decision-making (IDM, e.

Phenylmercury stress induces root tip swelling through auxin homeostasis disruption.

We previously reported that in Arabidopsis, the phytochelatin-mediated metal-detoxification machinery is also essential for organomercurial phenylmercury (PheHg) tolerance. PheHg treatment causes severe root growth inhibition in cad1-3, an Arabidopsis phytochelatin-deficient mutant, frequently accompanied by abnormal root tip swelling. Here, we examine morphological and physiological characteristics of PheHg-induced abnormal root tip swelling in comparison to Hg(II) stress and demonstrate that auxin homeostasis disorder in the root is associated with the PheHg-induced root tip swelling.

Extensive brainstem lesions in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): A case report.

Myelin oligodendrocyte glycoprotein antibody-associated disease is a group of central nervous system demyelinating disorders caused by autoantibodies. While myelin oligodendrocyte glycoprotein antibody-associated disease typically presents as optic neuritis and myelitis in adults, this case report details a patient with brainstem lesions. A 45-year-old male presented with episodes of vertigo, nystagmus, and diplopia in left lateral gaze, which had persisted for 2 months, accompanied by headache.

Naldemedine for Opioid-Induced Constipation in Patients With Cancer: A Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial.

Purpose: Opioid-induced constipation is the most frequent and non-self-limiting adverse effect of opioid analgesia, reducing adherence and interfering with pain relief. This clinical trial aimed to clarify the preventive effect of naldemedine versus placebo for constipation in patients with cancer starting regularly dosed strong opioids therapy.

Methods: This multicenter, double-blinded, randomized, placebo-controlled, confirmatory trial was conducted between July 2021 and May 2023 at four academic hospitals in Japan (Japan Registry of Clinical Trials identifier: jRCTs031200397).

Posterior Aspect Fracture of Tibia after Open Wedge Distal Tuberosity Osteotomy: A Case Report.

Introduction: Open wedge distal tuberosity osteotomy (OWDTO) was the surgical treatment in which tibial tuberosity was attached proximal fragment to avoid an increase in patellofemoral joint pressure. The current paper reported a case of post-operative posterior aspect fracture of the tibia as a rare complication after OWDTO.

Case Report: A 52-year-old Asian man had been performing OWDTO for medial knee osteoarthritis.