[Hepatitis non-A, non-B-associated substance in stool from patients with posttransfusion and sporadic hepatitis].

A hepatitis non-A,non-B-associated substance (HNANB-AS) excreted in feces has been detected by means of a sandwich radioimmunoassay using reconvalescent serum and IgG from patients with posttransfusion HNANB. 4380 stool filtrates from 1599 patients were screened with this assay. In patients with posttransfusion or sporadic acute and chronic HNANB the substance was detected with a mean frequency of 34%, in acute posttransfusion HNANB, where samples were screened at the beginning of the clinical symptoms, 71.

Therapy and monitoring of hypersiderosis in chronic renal insufficiency.

In RDT hemosiderosis appears to be an inevitable complication only in the small number of patients in need of frequent transfusions. To prevent clinical consequences (e.g.

The circadian rhythm of renal excretion in the rat: relationship between electrolyte and corticosteroid excretion.

In the rat, a circadian rhythm can be demonstrated in plasma levels and in urinary excretion rates of aldosterone and of corticosterone, reflecting rhythmic variations in adrenocortical secretion. There is also a circadian rhythm in the urinary excretion rates of sodium and of potassium in rats with unrestricted food consumption. The rhythmic pattern of potassium excretion seems to be controlled by the rhythm of corticosterone and/or aldosterone, whereas the rhythmic pattern of sodium excretion seems to be independent of adrenocortical secretion.