Publications by authors named "M Hida"
Introduction: The recently recommended activated clotting time (ACT) to be maintained at the initiation of and during cardiopulmonary bypass (CPB) is ≥480 s. However, the post-unfractionated heparin (UFH) administration ACT occasionally does not exceed 480 s. Therefore, in this study, we retrospectively evaluated the factors influencing post-heparin administration ACT before initiating CPB.
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- Hyper-IgE syndrome (HIES) is an inherited immune disorder marked by high IgE levels, chronic eczema, and recurrent staphylococcal infections.
- This study examined Moroccan patients likely suffering from HIES, focusing on their clinical and immunological features based on specific NIH criteria over a 25-year period.
- Findings revealed a wide range of symptoms, with eczema and skin infections being the most common, emphasizing the need for molecular analysis for accurate diagnosis and treatment in light of overlapping symptoms.
Article Synopsis
- * Diagnosis of osteopetrosis involves genetic testing and imaging techniques like X-rays and CT scans to confirm the condition.
- * A case study is presented of a 13-year-old boy in Morocco whose osteopetrosis was identified through unusual symptoms and confirmed via CT imaging, highlighting challenges in accessing medical care.
Article Synopsis
- - The study compared mitochondrial morphology and gene expression in liver samples from patients with biliary atresia (BA), infantile cholestasis (IC), and normal liver (NL) to determine their prognostic indicators.
- - Results showed that levels of heat shock protein 60 (HSP60) were significantly lower in BA and IC compared to NL, suggesting a correlation between HSP60 levels and liver health post-surgery (portoenterostomy).
- - Transmission electron microscopy revealed that BA patients had more mitochondrial abnormalities compared to IC and NL, indicating that mitochondrial dysfunction might contribute to the disease's severity and potential outcomes following treatment.
Article Synopsis
- This study explores the relationship between central sensitization and neuroinflammation in knee osteoarthritis and sarcopenia, which has not been extensively researched.
- It involved 340 knee osteoarthritis patients and 129 healthy older adults, examining various pain and strength metrics to understand differences in central sensitization.
- Results showed that those with knee osteoarthritis reported higher signs of central sensitization, while sarcopenic individuals exhibited lower pressure pain thresholds, highlighting distinct pain mechanisms in these conditions.