Publications by authors named "M Hexel"
Background: The rotator cuff is known to consist of 2 macroscopically visible layers that have different biomechanical properties. Sometimes the inferior layer may be neglected during rotator cuff repair. However, it is controversial whether double-layer (DL) repair is superior to single-layer (SL) repair in terms of retear rate and outcome.
View Article and Find Full Text PDFArticle Synopsis
- Idelalisib enhances the generation of chimeric antigen receptor T (CART) cells by increasing the proportion of less-differentiated T cells, which improves their growth and longevity in patients.
- Idelalisib treatment leads to a decrease in exhaustion markers and alters CD4:CD8 ratios in CART cells from chronic lymphocytic leukemia (CLL) patients, making them more similar to those from healthy donors.
- In vivo tests in a mouse model show that idelalisib-treated CART cells have effective anti-tumor activity, suggesting that further research on idelalisib-based CART cell protocols could lead to better cancer treatments.
Aims: The purpose of the present study was to evaluate the impact of intravenous tranexamic acid on the reduction of blood loss, transfusion rate, and early post-operative clinical outcome in total shoulder arthroplasty.
Patients And Methods: A randomised, placebo-controlled trial which included 54 patients undergoing unilateral primary stemless anatomical or stemmed reverse total shoulder arthroplasty was undertaken. Patients received either 100 ml saline (placebo, n = 27), or 100 ml saline together with 1000 mg of tranexamic acid (TXA, n = 27) intravenously prior to skin incision and during wound closure.
Infections following arthroscopic rotator cuff repair: incidence, risk factors, and prophylaxis.
Knee Surg Sports Traumatol Arthrosc
February 2017
Purpose: The primary aim of the present study was to determine the incidence of infections following arthroscopic rotator cuff repair in a single department over a 10-year period. Secondary goals included the evaluation of potential risk factors for infections and to investigate the efficacy of perioperative antibiotic prophylaxis in the reduction of infectious complications.
Methods: A retrospective evaluation of 3294 all-arthroscopic rotator cuff repairs performed between 2004 and 2014 at a single institution was conducted to determine the rate of infection in all-arthroscopic rotator cuff repairs.
Purpose: The purpose of this study was to biomechanically evaluate suture-tendon interface and tissue holding of three sutures in torn and degenerated versus intact human rotator cuffs.
Methods: Sixty-three human rotator cuff tendons were divided into torn degenerated group (TDG), n = 21 and intact group (IG), n = 42. Ultimate tension load (UTL) and cyclic loading were tested for three arthroscopic sutures: simple, horizontal, and massive cuff sutures (MCS).