Are PROMs sufficient to record late outcome of breast cancer patients treated with radiotherapy? A comparison between patient and clinician reported outcome through an outpatient clinic after 10years of follow up.

Aim: To investigate whether breast cancer patients' visits to an outpatient clinic for late outcome (OCLO) can be replaced by patient reported outcome measures (PROMs), by comparing late toxicity scored at the OCLO with PROMs.

Methods: All breast cancer patients treated in our institute with adjuvant radiotherapy 10-11years ago were invited to visit the OCLO, and for filling out PROM-questionnaires. Concordance rate between PROMs and OCLO-reported outcome and the percentage of patients with ≥2 degrees difference in toxicity level between patient and clinician was assessed.

Sensitivity to spatiotemporal combined luminance and chromaticity contrast.

Contrast-detection thresholds for various combinations of chromaticity and luminance differences were obtained for spatiotemporal square-wave modulation of a yellow field. The results are expressed in terms of excitation of the Vos-Walraven R,G primaries. For every spatiotemporal frequency the thresholds can be approximated by an ellipse in the red-green plane.

Influence of the target size on the deterction threshold for luminance and chromaticity contrast.

The effect of the target size on the detecton of luminance and chromaticity flicker and gratings was studied. Discrimination ellipses in a luminance-chromaticity plane were determined with square test areas subtending from 1/4 degree to 1 degree. Pure luminance modulation thresholds and pure chromaticity modualtion thresholds were obtained from square targets subtending from 1/16 degree to 2 degree.