Publications by authors named "M Herrera-Hernandez"
Purpose: To develop Mexico's first methodologically rigorous clinical practice guideline for the management of adult overweight and obesity. The target audiences are interdisciplinary healthcare professionals across healthcare systems who are the first point of contact for patients with obesity in Mexico, patients, and health system decision makers.
Recent Findings: A review of recent international obesity clinical practice guidelines and an expert consensus process identified: i) common recommendations appropriate for implementation in Mexico and ii) knowledge gaps requiring the formulation of new recommendations.
Characterization of Extractable and Non-Extractable Phenols and Betalains in Berrycactus () and Its Chemoprotective Effect in Early Stage of Colon Cancer In Vivo.
Rosa Iris Godínez-Santillán Aarón Kuri-García Iza Fernanda Ramírez-Pérez María Guadalupe Herrera-Hernández Santiaga Marisela Ahumada-Solórzano
Antioxidants (Basel)
September 2024
Article Synopsis
- - The study explored the bioactive compounds and antioxidant potential in extractable (EP) and non-extractable (NEP) polyphenol fractions of berrycactus (BC), identifying 33 polyphenols, some of which were new to BC.
- - Male Sprague Dawley rats were used to assess the effects of BC and its residue (BCR) on early colon cancer development induced by AOM/DSS, revealing that BC and BCR helped reduce colonic damage and aberrant crypt foci.
- - The NEP fractions, especially those treated with HCl, showed strong antioxidant activity and higher total phenolic content, indicating that these compounds could play a role in preventing early colon carcinogenesis while maintaining
Article Synopsis
- Plant viruses like brome mosaic virus and cowpea chlorotic mottle virus can be purified using techniques like PEG precipitation and ultracentrifugation.
- Changes in ionic strength and alkaline pH lead to the disassembly of these viruses into coat protein subunits, which can then be reassembled into stable virus-like particles (VLPs).
- VLPs are promising in nanomedicine for their ability to protect and deliver RNA and can be chemically modified for targeted drug delivery in various therapeutic applications.
New insights into the molecular mechanism of rhodopsin retinitis pigmentosa from the biochemical and functional characterization of G90V, Y102H and I307N mutations.
María Guadalupe Herrera-Hernández Neda Razzaghi Pol Fernandez-Gonzalez Laia Bosch-Presegué Guillem Vila-Julià
Cell Mol Life Sci
January 2022
Article Synopsis
- Mutations in the rhodopsin protein Y102H and I307N are significant contributors to retinal degeneration, and researchers are studying them as models to understand this process in humans.
- Both mutations destabilize the inactive form and stabilize the active form of rhodopsin, impacting how the receptor functions in signal transduction.
- The study suggests that these mutations alter the flexibility of certain structural elements of rhodopsin, affecting its ability to bind retinal and activate related signaling processes.