Publications by authors named "M Heppe-Montero"
Introduction: Cerebral and cerebellar pseudoatrophy is a rare adverse effect of valproic acid (VPA) that we need to be aware of, due to its diagnostic and therapeutic implications.
Case Report: We report three cases of children between 5 and 9 years old, with epilepsy and previous normal brain magnetic resonance imaging, who were taking the drug at correct doses. Pseudoatrophy manifests subacutely with symptoms and images of cerebral and/or cerebellar atrophy, reversible after drug withdrawal.
Article Synopsis
- RSV is a significant cause of hospitalization and death in adults, particularly those aged 60 and older, with 9.1% of ALRTI hospitalizations linked to RSV and 3.0% to influenza in Spain from 2012 to 2020.
- Hospitalization rates for RSV were estimated at 1.69 per 100,000 for the elderly, compared to 2.72 for influenza, indicating a higher impact of influenza in terms of hospital admissions.
- However, RSV patients exhibited higher in-hospital mortality rates at 7.91%, compared to 6.91% for influenza, especially among older and frail individuals, highlighting a critical health risk associated with RSV.
Background: Respiratory syncytial virus (RSV) is a major cause of acute lower respiratory tract infection (ALRI) leading to infant hospitalization, morbidity and postnatal mortality in children younger than 5 years of age worldwide. The aim of this study was to collect data on hospitalizations for RSV-related ALRI in children in Spain from 2012 to 2018.
Methods: We used the discharge reports from the Minimum Basic Data Set (MBDS) to retrospectively analyze hospital discharge data in children ≤ 14 years of age with a diagnosis of acute lower respiratory tract infection, based on the ICD-9-CM and ICD-10-CM diagnosis codes, from 2012 to 2018.
Bronchiolitis represents a heavy burden of disease in children under 2 years of age in our society due to the high infectivity of the Respiratory Syncytial Virus [RSV] and the vulnerability of the youngest children.The objective of this retrospective epidemiological study was to show the burden of severe bronchiolitis in Spain through population-based estimates of hospitalizations due to bronchiolitis in children up to 24 months old during a 6-year period (2012-2017).A total of 100,115 cases of bronchiolitis required hospitalization in Spain from 2012 to 2017.
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