Publications by authors named "M Henry-Feugeas"
Background: Susac syndrome (SuS) is a rare immune-mediated microangiopathy with potential disabling evolution. We aimed to analyze brain microstructural damage through diffusion tensor imaging (DTI) in SuS and determine its association with poor outcomes.
Method: CarESS study is a prospective multicenter national cohort study of patients with SuS.
Article Synopsis
- Nonreversible hearing loss (HL) is a significant issue for patients with Susac syndrome (SuS), prompting a study to identify risk factors associated with HL in these individuals.* -
- The CARESS study involved 36 patients diagnosed with SuS, revealing that 52.8% experienced severe HL after a median follow-up of about 52 months, with many showing cochleovestibular involvement at diagnosis.* -
- The study concluded that the use of immunosuppressive (IS) drugs at diagnosis may lower the odds of developing severe HL, suggesting these drugs should be regularly considered in SuS treatment.*
Article Synopsis
- Susac syndrome (SuS) is a rare disease affecting the brain, retina, and inner ear, and the study aimed to see if the amount of brain lesions at the start could predict patient outcomes.* -
- Conducted in France from 2012 to 2019, the study analyzed 23 patients using MRI to look at the characteristics of brain lesions at diagnosis and during follow-up.* -
- Results showed that despite differences in the number of brain lesions (low vs. high), there was no significant impact on disability or overall outcomes for patients with SuS.*