Publications by authors named "M Hedouin"
Article Synopsis
- The text discusses the necessity of using excess butyllithium (n-BuLi) for effective directed ortho-lithiation of trifluoromethyl sulfoximine.
- It details low-temperature NMR analysis revealing that the first deprotonation produces dimeric and tetrameric N-lithiated sulfoximines in a specific ratio (93:7).
- The study identifies and characterizes six different species formed during the reaction, including three significant aggregates of dilithiated sulfoximine with varying solvation by THF molecules.
Scalar coupling in organolithium systems can provide access to useful structural and dynamic informations. In this work, we propose a robust method for the accurate measurement of the effective J coupling constant in tetramerics alkyllithium aggregates. This crucial information, unavalaible to date, gives a simple access to various structural factors, including the dynamics, solvation and the operative steric hindrance of alkyl chains.
View Article and Find Full Text PDFBackground: Intraoperative combinations of volatile and opioid agents are used to achieve unconsciousness, hypnotic sparing, haemodynamic stability and uneventful recovery. This study describes the influence of different remifentanil concentrations on these variables when combined with desflurane during abdominal surgery.
Methods: Sixty-one healthy adult patients were randomly allocated to one of five predefined remifentanil target concentrations (3, 5, 7, 10 or 15 ng ml(-1)).
We report a systematic experimental investigation of the mechanism of desorption of chlorobenzene molecules from the Si(111)-(7 x 7) surface induced by the STM at room temperature. We measure the desorption probability as a function of both tunneling current and a wide range of sample bias voltages between -3 V and +4 V. The results exclude field desorption, thermally induced desorption, and mechanical tip-surface effects.
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