Phenolphthalein Conjugated Schiff Base as a Dual Emissive Fluorogenic Probe for the Recognition Aluminum (III) and Zinc (II) Ions.

In this study, a new phenolphthalein derivative, FFIZNA, has been planned and successfully prepared in an uncomplicated way. The probe FFIZNA could selectively monitor Al and Zn among other relevant cations with diverse colors through a turn-on emission response in EtOH:HEPES (9/1;v/v) media owing to the chelation enhanced fluorescence (CHEF), prevention of ESIPT, -C=N- isomerization and PET of the probe FFIZNA. The interactions of Al and Zn with the probe FFIZNA were confirmed by emission spectroscopy, Job's plot and H-NMR titration substantiated 1:2 reaction stoichiometry between FFIZNA and Al and Zn.

The pharmacists' ability to use pressurized metered-dose inhalers with a spacer device and factors affecting it.

The aim of this study is to evaluate the pharmacists' ability to use pMDIs with a spacer device and the factors that affect this ability. Face to face interviews were conducted with the pharmacists. A nine item questionnaire was completed and the checklist for how to use pMDIs with a spacer device was filled out.

Analysis of geographical variations in the epidemiology and management of non-valvular atrial fibrillation: results from the RAMSES registry.

Objective: This study aimed to determine the differences in terms of demographic characteristics and preferred stroke prevention strategies for patients with non-valvular atrial fibrillation living in seven geographical regions of Turkey.

Methods: In total, 6273 patients were enrolled to this prospective, observational RAMSES study. The patients were divided into seven groups based on the geographical region of residence.

The Time in Therapeutic Range and Bleeding Complications of Warfarin in Different Geographic Regions of Turkey: A Subgroup Analysis of WARFARIN-TR Study.

Background: The time in therapeutic range values may vary between different geographical regions of Turkey in patients vitamin K antagonist therapy.

Aims: To evaluate the time in therapeutic range percentages, efficacy, safety and awareness of warfarin according to the different geographical regions in patients who participated in the WARFARIN-TR study (The Awareness, Efficacy, Safety and Time in Therapeutic Range of Warfarin in the Turkish population) in Turkey.

Study Design: Cross-sectional study.

Real-World Clinical Characteristics and Treatment Patterns of Individuals Aged 80 and Older with Nonvalvular Atrial Fibrillation: Results from the ReAl-life Multicenter Survey Evaluating Stroke Study.

Objectives: To compare the clinical characteristics of and use of oral anticoagulant (OAC) therapy in individuals aged 80 and older with atrial fibrillation (AF) with those of individuals younger than 80 with AF in clinical practice.

Design: Observational study.

Setting: The ReAl-life Multicenter Survey Evaluating Stroke prevention strategies in Turkey trial (NCT02344901), a national observational registry.