Efficacy of Fetal Wharton's Jelly Mesenchymal Stem Cells-Derived Small Extracellular Vesicles in Metabolic Syndrome.

Background/objective: Metabolic syndrome (MetS) is characterized by abdominal obesity, increased blood pressure (BP), fasting blood glucose (FBG) and triglyceride levels, and reduced high-density lipoprotein (HDL) levels. This study aims to investigate the efficacy of the Wharton's jelly mesenchymal stem cells (WJMSCs)-derived small extracellular vesicles' (sEVs) preparations in managing MetS.

Method: Twenty-four rats were fed with a high-fat and high-fructose diet to induce MetS for 16 weeks and randomized into three groups ( = 8/group): a MetS Control group treated with normal saline, MetS Low Dose (LD) group treated with a LD of sEVs preparations (3 × 10 particle/rat), and MetS High Dose (HD) group treated with a HD of sEVs preparations (9 × 10 particles/rat).

Nonpharmacological Management of Dental Anxiety in the General Population and Individuals With Learning Disabilities: A Bibliometric Analysis.

Aims: Dental anxiety (DA) is reported among the general population, including individuals with learning disabilities (LDs). In many studies, nonpharmacological interventions have been applied to significantly improve DA among patients. This study aimed to examine publication trends and patterns in both populations to identify the current research trends and literature gaps.

[MRI-Ultrasound Fusion Targeted Transperineal Prostate Biopsy Under Local Anaesthesia Patient-Reported and Biopsy Outcomes: A Single Centre Cohort Study].

Objective: To compare the tolerability and feasibility of transrectal(TR) versus transperineal (TP) routes for prostate biopsy under local anaesthesia(LA). To assess the functional outcome and the complication of both procedures.

Method: s.

Factors affecting the quality of work life for industrial labour force: empirical evidence from a developing country.

The success of any organization requires a skilled, competent, and satisfied workforce. If the workforce can be provided with the necessary components to ensure a high quality of working life, they will become permanent assets. Various factors undoubtedly affect the quality of workers' work lives.

Evaluating applied security controls for safeguarding medical device-integrated electronic medical records.

Rationale, Aims, And Objectives: Medical device-integrated electronic medical records (MDI-EMR) pose significant challenges in ensuring effective usage, data security and patient safety. The complexities of MDI-EMR necessitate applying various security mechanisms to safeguard against cyber threats. Therefore, we evaluated cyber threats to MDI-EMR and the effectiveness of applied security controls using a proposed framework from sociotechnical and risk assessment perspectives.