Publications by authors named "M Hayakawa"
This study discusses disseminated intravascular coagulation (DIC) associated with solid cancers and various vascular abnormalities, both of which generally exhibit chronic DIC patterns. Solid cancers are among the most significant underlying diseases that induce DIC. However, the severity, bleeding tendency, and progression of DIC vary considerably depending on the type and stage of the cancer, making generalization difficult.
View Article and Find Full Text PDFAim: Hypothermia-associated pancreatitis lacks comprehensive understanding owing to limited studies exploring its mechanism, epidemiology, risk factors, and outcomes. We aimed to investigate the frequency, characteristics, and predictive factors associated with the development of acute pancreatitis in patients with accidental hypothermia.
Methods: This study comprised a post hoc analysis of data from a multicenter prospective observational study (ICE-CRASH study) conducted in 36 tertiary emergency hospitals in Japan.
Two new benzene-containing polyketides, cryptoic acids A (1) and B (2), along with a new acylated diketopiperazine designated cyclocryptamide (3), were isolated from the culture extract of Cryptosporangium sp. YDKA-T02. The absolute configuration of amino acid components in 3 was determined by Marfey's method.
View Article and Find Full Text PDFArticle Synopsis
- Re-occlusion and thrombus formation after mechanical thrombectomy in stroke patients can lead to worse outcomes, but early antiplatelet therapy (APT) may help prevent these issues.
- Current guidelines recommend waiting to use APT after intravenous thrombolysis, which complicates treatment for large vessel occlusion strokes.
- A study of 164 patients in Japan suggests that starting APT early post-thrombolysis is safe, with no significant differences in hemorrhagic events or mortality compared to those who started APT later or not at all.
Background: Death in the early phase of trauma is primarily attributable to uncontrolled bleeding exacerbated by trauma-induced coagulopathy (TIC). A comprehensive synthesis of the available evidence on interventions for TIC is needed.
Methods: We conducted a systematic review and meta-analysis of blood component products and tranexamic acid administrations for severe trauma patients with TIC.