Publications by authors named "M Hatayama"
Background: Accumulating evidence has suggested that neuropeptides such as orexin, ghrelin, or oxytocin act centrally in the brain to regulate intestinal barrier function through the vagus nerve. It has been reported that the vagal cholinergic anti-inflammatory pathway was blocked by splenectomy. In the present study, we therefore examined the effect of splenectomy on neuropeptides-induced improvement of increased intestinal permeability.
View Article and Find Full Text PDFAn x-ray multilayer mirror on a spherical substrate designed for near-normal incidence with a photon energy of ∼738 eV (F Heα) was procured and tested. This device is intended to be used for in-flight radiography of the shell in inertial confinement fusion experiments with cryogenic targets on the OMEGA laser at the Laboratory for Laser Energetics. Experiments in self-emission on a small (∼10 J) laser system showed that the reflectivity of the mirror is high enough to record an image at laser energies as low as 0.
View Article and Find Full Text PDFArticle Synopsis
- Various biomarkers have been studied to predict outcomes in allogeneic hematopoietic cell transplantation (HCT), but most prior research focused on single effects rather than a comprehensive analysis of multiple markers.
- The study surveyed 32 candidate biomarkers from hematological, biochemical, and immunological sources in patients undergoing HCT, aiming to identify those significantly predicting survival and other complications.
- Results revealed six promising markers, including CRP and IL2R ratios, which were validated internally and shown to reliably predict overall survival, relapse, and non-relapse mortality in the patient population.
We describe the case of a 36-year-old man diagnosed with human immunodeficiency virus (HIV) following prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia. The patient had a complication of pneumocystis pneumonia. Upon initiating highly active antiretroviral therapy, we monitored HIV RNA levels, CD4+ T-cell count, SARS-CoV-2 viral load, and IgG antibodies against SARS-CoV-2.
View Article and Find Full Text PDFBackground And Aims: Multiple myeloma (MM), a neoplasm of plasma cells (PCs), is a highly heterogeneous disease with multifocal dissemination throughout the body. Minimal residual disease (MRD) detected using PCs in bone marrow (BM) is important for MM management; however, frequent invasive examinations impose a significant burden on patients.
Methods: Analysis using plasma cell-free DNA (cfDNA) might represent an alternative tool for disease monitoring.