Publications by authors named "M Hashemzaei"
Hesperidin neuroprotective effects against carbon monoxide-induced toxicity in male rats.
Naunyn Schmiedebergs Arch Pharmacol
October 2024
Carbon monoxide (CO) is produced via incomplete combustion of fossil fuels and it may cause long-term neurological sequel upon exposure. Hesperidin (HES), a flavanone glycoside found in citrus plants, exerts diverse beneficial health effects. The present study mechanistically examined the neuroprotective effects of HES in CO-poisoned rats.
View Article and Find Full Text PDFAim And Background: Trinitroglycerin (TNG) is a remarkable NO-releasing agent. Here, we synthesized TNG based on chitosan Nanogels (Ngs) for ameliorating complications associated with high-dose TNG administration.
Method: TNG-Ngs fabricated through ionic-gelation technique.
Immune thrombocytopenic purpura (ITP) is an autoimmune disorder determined by immune-mediated platelet demolition and reduction of platelet production. Romiplostim is a new thrombopoiesis motivating peptibody that binds and stimulates the human thrombopoietin receptor the patent of which was registered in 2008. It is used to treat thrombocytopenia in patients with chronic immune thrombocytopenic purpura.
View Article and Find Full Text PDFArticle Synopsis
- Arsenic poisoning is a significant global health issue known to cause various serious health problems, including cancer and liver damage, leading researchers to explore protective effects of curcumin.
- In experiments using isolated rat liver cells, curcumin was applied in different concentrations before arsenic exposure to determine its protective properties against cell damage.
- Results indicated that low doses of curcumin (2 µM) effectively reduced oxidative stress and cell damage caused by arsenic, while higher doses did not show similar protective effects and may even worsen the situation.